Soy Derived Phosphatidylserine; Nutrient content 70%; Free-flowing
powder, Easy formulated, Synthesis and metabolism
BioPS® 70% Soy Derived Phosphatidylserine
Phosphatidylserine (PS), a ubiquitous, endogenously occurring
phospholipid, is the major acidic phospholipid in the brain. PS and
other phospholipids make up the basic structural components of the
cell membrane. These membrane phospholipids playan important role
in cell-to-cell communication and transfer of biochemical messages
into the cell, which trigger cellular responses.
The proper functioning of these processes is of ultimate
importance, especially in the central nervous system. It is
theorized that PS enhances cellular metabolism and communication by
influencing the fluidity of cell membranes.1-4 Oral supplementation of PS has been shown to affect neuronal
membranes, cell metabolism, and specific neurotransmitter systems,
including acetylcholine, norepinephrine, serotonin, and dopamine.1-4 Numerous clinical trials have established that PS exerts
significant benefit for cognition, especially those functions that
tend to decline with age, including memory,learning, vocabulary
skills, and concentration.5
1. Crook TH, Tinklenberg J 1. , Yesavage J, et al. Effects of
phosphatidylserine in age-associated memory impairment. Neurology
2. Amaducci L, Crook TH, Lippi A, et al. Use of phosphatidylserine
in Alzheimer's Disease. Ann N Y Acad Sci 1991;640:245-249.
3. Cenacchi T, Bertoldin T, Farina C, et al. Cognitive decline in
the elderly: a double-blind, placebo-controlled multicenter study
on efficacy of phosphatidylserine administration. Aging (Milano)
4. Crook T, Petrie W, Wells C, Massari DC. Effects of
phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull
5. Kidd PM. Phosphatidylserine; membrane nutrient for memory. A
clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
Synthesis and metabolism in the brain
PS synthesis and metabolism in the brain. PS is synthesized by
replacement of the choline group of PC by serine in a reaction
catalyzed by PSS1, and also by replacement of the ethanolamine
group of PE by serine in a reaction catalyzed by PSS2. These
synthetic reactions occur in the endoplasmic reticulum. PS is
decarboxylated to PE in the mitochondria by PS decarboxylase (PSD).
The phosphatidylethanolamine methyltransferase (PEMT) reaction that
utilizes Sadenosylmethionine (SAM) to convert PE to PC is indicated
as a dashed arrow because more recent findings have demonstrated
that previously reported methylation activity in the brain [1,2] is quantitatively insignificant[3,4].
 Pynn CJ, Henderson NG, Clark H, Kostner G, Bernhard W, Postle AD.
Specificity and rate of human and mouse liver and plasma
phosphatidylcholine synthesis analyzed in vivo. J Lipid Res
 Mozzi R, Porcellati G. Conversion of phosphatidylethanolamine
to phosphatidylcholine in rat brain by the methylation pathway.
FEBS Lett 1979;100:363–6.
 Vance JE, Pau D, Campenot RB, Bussière M, Vance DE. Evidence
that the major membrane lipids except cholesterol, are made in
axons of cultured rat sympathetic neurons. J Neurochem
 Vance DE. Phospholipid methylation in mammals: from
biochemistry to physiological function. Biochim Biophys Acta
|Product name||BioPS® 70% Soy Derived Phosphatidylserine|
|Appearance||Light Yellow to Brown Powder|
|Packaging||5kg per bag,10kg per carton or Customizable|
|Peroxide Value||≤5.0meq/kg(Iodide titration)|
|Solvents Used||Ethanol & water|
|Total Plate Count||≤1,000cfu/g(USP)|
|Yeast & Mold||≤100cfu/g(USP)|
|Aflatoxin(B1, B2, G1, G2)||≤20ppb(HPLC-FLD)|
|Shelf Life||2 years from date of manufacture|
|Storage conditions||Store in tightly closed containers at room temperature. Protected
from moisture and pest infestation.|
1.Q: Is this made from GMO-free soy?
A: Yes! Our product (PhosphatidylSerine powder) is Non-GMO, Non- solvent residues, identity preserved and Halal certification.
2.Q: Any other sources?
A: sunflower seed, marine fish roe
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